Article Abstract

The direct oral anticoagulants in patients with and without liver disease

Authors: Paulina Chinchilla-López, Héctor Baptista-González, Nicolas M. Intagliata, Patrick G. Northup, Stephen H. Caldwell, Nahum Méndez-Sánchez


Anticoagulants are frequently prescribed agents for the prevention and treatment of many cardiovascular conditions. A large number of clinical studies have shown that these agents can prevent or treat acute or chronic thromboembolic diseases. However, the most important complication of treatment with anticoagulant agents is hemorrhage, which may be serious, may cause long-term debilitating disease, or may even be life threatening (1).