Article Abstract

Proton pump inhibitors and hepatic encephalopathy: fly quiet in the eye of the storm

Authors: Antonio Picardi, Umberto Vespasiani-Gentilucci


Portal hypertension (PHT) is the ominous root of the most demanding manifestations of end stage liver disease or cirrhosis, mostly independent from the etiology of chronic liver disease. The multiform clinical manifestations of PHT include upper digestive tract bleeding, ascites, and hepatic encephalopathy (HE) (1).