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Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: an unmet need finally met?

   
@article{AMJ3765,
	author = {Farhan Gohar and Dhiraj Tripathi},
	title = {Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: an unmet need finally met?},
	journal = {AME Medical Journal},
	volume = {2},
	number = {4},
	year = {2017},
	keywords = {},
	abstract = {Non-selective beta blocker (NSBB) therapy remains the front runner in the treatment of portal hypertension. Over the years, our understanding of their mechanisms of action, both haemodynamic and non-haemodynamic, has evolved. Variceal bleeding, an inevitable consequence of portal hypertension, accounts for 10% of all admissions with gastrointestinal bleeding, and has an inpatient mortality of 15% and 1 year mortality of up to 40% (1). Reducing the risk of the development of varices (pre-primary prophylaxis) and the first variceal bleed (primary prevention) are therefore important clinical goals.},
	issn = {2520-0518},	url = {https://amj.amegroups.org/article/view/3765}
}