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Trimethylamine N-oxide and platelets aggregation: insufficient evidence for causal inference in thrombosis

   
@article{AMJ4016,
	author = {Rima Obeid},
	title = {Trimethylamine N-oxide and platelets aggregation: insufficient evidence for causal inference in thrombosis},
	journal = {AME Medical Journal},
	volume = {2},
	number = {8},
	year = {2017},
	keywords = {},
	abstract = {Trimethylamine N-oxide (TMAO) is an amine oxide generated in the liver from nutrients such as choline, betaine, or carnitine via an intermediate gut-bacteria driven metabolite, trimethylamine (TMA). Recently, Zhu et al. conducted a 2-month open-, non-placebo controlled intervention in vegetarians and omnivores using 450 mg total choline/day (1). Zhu et al. reported a significant increase in plasma TMAO concentrations (from 2.5 to 36.4 M in omnivores and from 2.6 to 27.2 M in vegetarians).},
	issn = {2520-0518},	url = {https://amj.amegroups.org/article/view/4016}
}