TY - JOUR AU - Evers, Lauren AU - Patel, Dhyanesh PY - 2018 TI - Proton pump inhibitor non-responsive gastroesophageal reflux disease: unraveling an enigma? JF - AME Medical Journal; Vol 3 (February 2018): AME Medical Journal Y2 - 2018 KW - N2 - Gastroesophageal reflux disease (GERD) affects 10–20% of adults in Western countries (1,2) and 13% of Americans use medications for GERD at least twice weekly (3). In the USA alone, it is estimated that the annual direct and indirect costs incurred due to GERD is approximately $10 billion (4). UR - https://amj.amegroups.org/article/view/4281